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A Sustained Record of Peer-Reviewed Publications

Over a period of more than five years, members of this group have collectively produced a high volume of peer-reviewed publications, with consistent output year after year. This body of work reflects long-term commitment to rigorous methodology, reproducibility, and clinically relevant research questions.

1.

Efficacy of Magseed Localization for Non-palpable Breast Lesions: A Systematic Review and Meta-analysis

Lamees M Al Darwashi , May Y Hajeir , Rashad M Abdelrahman , Emma J Nordahl , Abdullah R Ayesh , Ahmed Ghani , Marios Alogakos , Christian A Than , Hayato Nakanishi , Suaad A Al Aghbari 

Anticancer Research, DOI: 10.21873/anticanres.17919

2.

Meta-analytic evaluation of complications and longevity of bone-anchored prostheses in lower extremity amputees: does design matter?

Hugh Milchem , Yasmine J Khair , Maamoun Adra , Shayndhan S Sivanathan , Shreehari Suresh , Dilip K Vankayalapati , Aslam Mohamed Haroon , Christian A Than , Nadim Tarazi , Hayato Nakanishi , Peter J Smitham

 Musculoskeletal Surgery, DOI: 10.1007/s12306-026-00946-9

3.

Thyroidectomy Outcomes in Older Adults: A Systematic Review and Meta-Analysis

Ahmed Ghani , Abdullah R Ayesh , Harisanth Rajaram , Sherwin M Ganegoda , Marios Alogakos , Alma Sato , Karl Hage , Christian A Than , Hayato Nakanishi , Joyce Shin , Gustavo Romero-Velez

JAMA Otolaryngology Head Neck Surgery, DOI: 10.1001/jamaoto.2025.5345

4.

Assessing the Safety and Efficacy of Picosecond Alexandrite Lasers in the Management of Melasma: A Systematic Review and Meta-Analysis of Randomised Control Trials

Kangjie R Chua , Dilip K Vankayalapati , M Zaid Shami , Valeria Antoniou , Emma J B Nordahl , Kowthar Abdul-Aziz , Laith Bayan , Sum-Yu C Lee , Hayato Nakanishi , Christian A Than , Davin Lim 

Australian Journal of Dermatology, DOI: 10.1111/ajd.70051

1.

The effect of iodine solution in total thyroidectomy for patients with Graves disease: A meta-analysis

Aslam Mohamed Haroon , Ahmed Ghani , Abdullah R Ayesh , Maria M Witkowiak , Marios Alogakos , James Burns , Christian A Than , Basim Wahba , Hayato Nakanishi , Travis McKenzie 

Surgery, DOI: 10.1016/j.surg.2025.109926

2.

Grayson’s Technique for Presurgical Nasoalveolar Molding (PNAM) in Unilateral Cleft Lip and Palate: A Systematic Review and Single-Arm Meta-Analysis

Laith Bayan , Emma Nordahl , Kelson Huynh , Nathanael Qe Yap , Ismail Ozgenc , Anna Csiky , Sum-Yu Christina Lee , Alma Sato , Christian A Than , Hayato Nakanishi , Shelagh A Cofer 

The Cleft Palate Craniofacial Journal, DOI: 10.1177/10556656251395936

3.

Isolated Flexor Hallucis Longus Tendon Transfer for Chronic Achilles Tendon Rupture: Systematic Review and Meta-Analysis

Yasmine J Khair , Hugh Milchem , Maamoun Adra , Anthony Fong , Thant Htoo Nyan , Shayndhan Sivanathan , Hayato Nakanishi , Christian A Than , Nadim Tarazi , Constantinos Loizou , Marcus Mumme 

Healthcare, DOI: 10.3390/healthcare13212751

4.

Long-term outcomes of Roux-en-Y gastric bypass in the adolescent population: a systematic review and single-arm meta-analysis

Baraa Saad , Kenan Rahima , Mohammed M Mourad , Dilip K Vankayalapati , Omotayo Segun-Omosehin , Hafsa O Sulaiman , James W F Burns , Hayato Nakanishi , Christian A Than , Akheel A Syed , Bilal Alkhaffaf 

Surgery For Obesity and Related Disease, DOI: 10.1016/j.soard.2025.09.003

5.

Laparoscopic versus open splenectomy in non-traumatic pediatric patients: a systematic review and meta-analysis

Alma Sato , Marios Alogakos , James W F Burns , Megan Roberts , Dafni-Stravroula Grammenou , Ebaney Ghotra , Emily E Lugard , Charbel Chidiac , Christian Aloysius Than , Hayato Nakanishi , Shaun M Kunisaki 

Pediatric Surgery International, DOI: 10.1007/s00383-025-06208-2

6.

Comparative Outcomes of Septal Extension versus Columellar Strut Grafts for Nasal Tip Stabilization and Positioning in Rhinoplasty: A Systematic Review and Meta-analysis

Ismail Ozgenc , Dana Alzoubi , Dilip K Vankayalapati , Laith Ali Bayan , Sum-Yu Christina Lee , Kelson Huynh , Annah Waqasi , Hayato Nakanishi , Annakan V Navaratnam 


Facial Plastic Surgery, DOI: 10.1055/a-2689-1496

7.

Enucleation for insulinoma: consolidating evidence through systematic review and meta-analysis

Marios Alogakos , Hayato Nakanishi , Dimitrios I Athanasiadis , Soroush Farsi , Shreehari Suresh , Maria M Witkowiak , Fatma A M Abdulsalam , Christian A Than , Travis J McKenzie , Eugene P Ceppa 

Surgical Endoscopy, DOI: 10.1007/s00464-025-12099-0

8.

Clinical impact of obesity on thyroidectomy outcomes: A systematic review and meta-analysis

Ahmed Ghani , Lamees M Al Darwashi , May Y Hajeir , Abdullah R Ayesh , Maria M Witkowiak , Marios Alogakos , Karl Hage , Christian A Than , Hayato Nakanishi , Joyce Shin , Gustavo Romero-Velez 

Surgery, DOI: 10.1016/j.surg.2025.109598

9.

Characterizing Spinal Decompression for Foot Drop Caused by Lumbar Degenerative Disease: A Systematic Review and Meta-Analysis of Cohorts

Christian A Than , May Y Hajeir , Lamees M Al Darwashi , Kelly Silnes , Aslam Mohamed Haroon , Angelique K Valiotis , Diana Shibib , Yasmine J Khair , Hugh Milchem , Persidiu Iancu , Zaher Dannawi 

Journal of Clinical Medicine, DOI: 10.3390/jcm14134470

10.

The effect of early nipple stimulation on third stage of labour duration and estimated blood loss: A systematic review and meta-analysis

Zoe Y Zervides , Maria M Witkowiak , Dana O Alzoubi , Reem B Zalloum , Natalie E Bourdakos , Fatma A M Abdulsalam , Hayato Nakanishi , Christian A Than , Shavi Fernando , Sir Sabaratnam Arulkumaran 

Midwifery, DOI: 10.1016/j.midw.2025.104478

11.

Operative Versus Nonoperative Management of High-Grade Acromioclavicular Injuries: A Systematic Review and Meta-Analysis

Maamoun Adra , Aslam Mohamed Haroon , Hugh Milchem , Shreehari Suresh , Yasmine J Khair , Haya El Merkabaoui , Rania Mansour , Mohamed Kamal M Youssef , Hayato Nakanishi , Christian Than , Rami Estfan , Greg Packer 

Cureus,  DOI: 10.7759/cureus.76682

12.

Safety and efficacy of transcatheter arterial embolization in renal angiomyolipomas: a systematic review and meta-analysis

Shahid Miangul , Karen Smayra , Liranne Bitton , Reem B Zalloum , Nathanael Q E Yap , Baraa Saad , Rangish Yuvaraj , Marios Alogakos , Hayato Nakanishi , Christian A Than , Aneeta Parthipun

BMC Nephrology, DOI: 10.1186/s12882-024-03893-4

13.

Healing Rates and Dressing Frequency of Silver Foam Dressings in Paediatric Burns: A Systemic Review and Meta-Analysis

Nathanael Q E Yap , Dilip K Vankayalapati , Sum-Yu C Lee , Hafsa O Sulaiman , Alma Sato , M Zaid Shami , Valeria Antoniou , James W F Burns , Hayato Nakanishi , Christian A Than , Graeme Southwick 

European Burn Journal, DOI: 10.3390/ebj6010003

14.

Benefits of negative pressure wound therapy in skin grafts: A systematic review and meta-analysis of randomised controlled trials

Sum-Yu Christina Lee , Laith Bayan , Alma Sato , Dilip K Vankayalapati , Valeria Antoniou , M Zaid Shami , Hafsa Omer Sulaiman , Nathanael Yap , Hayato Nakanishi , Christian A Than , Kai Yuen Wong 

Journal of plastic, reconstructive & aesthetic surgery,
DOI:  10.1016/j.bjps.2025.01.036

15.

Diagnostic Accuracy of Four-Dimensional Computed Tomography in Preoperative Localization of Primary Hyperparathyroidism After Negative or Inconclusive Sestamibi: A Systematic Review and Meta-analysis

Karen Smayra, Shahid Miangul, Joseph Nasr, Alma Sato , Sum-Yu C Lee , Liranne Bitton , Nour El Ghazal, Kyle G Alexander , Hayato Nakanishi, Christian A Than, Raman Uberoi 

Journal of Computer Assisted Tomography,
DOI:  10.1097/RCT.0000000000001689

16.

Prolonged Taping with Exercise Therapy for Patellofemoral Pain in Adults: A Systematic Review and Single-Arm Meta-Analysis

Christian A Than , Maamoun Adra , Tom J Curtis , Yasmine J Khair , Hugh Milchem , Sum-Yu C Lee , Goktug Şanli , Karen Smayra , Hayato Nakanishi , Zaher Dannawi , Belinda R Beck 

Journal of Clinical Medicine, DOI: 10.3390/jcm13237476

1.

NSAIDs and Corticosteroids for the Postoperative Management of Age-Related Cataract Surgery: A Systematic Review and Meta-analysis

Joe El Haddad , Nader Al Sabbakh , Marie Michele Macaron , Hashim Shaaban , Natalie E Bourdakos , Ao Shi , Baraa Saad , Hayato Nakanishi , Christian A Than , Yassine J Daoud 

American Journal of Ophthalmology, DOI: 10.1016/j.ajo.2023.09.027

2.

Long-Term Outcomes of Mechanical Versus Bioprosthetic Aortic Valve Replacement: A Systematic Review and Meta-Analysis

Dilip K Vankayalapati , Omotayo Segun-Omosehin , Nour El Ghazal , Rohan Suresh Daniel , Joe El Haddad , Rania Mansour , Nathanael Yap , Shahid Miangul , Hayato Nakanishi , Christian A Than 

Cureus, DOI: 10.7759/cureus.52550

3.

Clinical outcomes of outpatient thyroidectomy: A systematic review and single-arm meta-analysis

Hayato Nakanishi , Rongzhi Wang , Shahid Miangul , Grace E Kim , Omotayo A Segun-Omosehin , Natalie E Bourdakos , Christian A Than , Benjamin E Johnson , Herbert Chen , Andrea Gillis 

American Journal of Surgery, DOI: 10.1016/j.amjsurg.2024.02.037

4.

Twin pregnancy and postpartum haemorrhage: a systematic review and meta-analysis

Fatma A M Abdulsalam , Natalie E Bourdakos , James W F Burns , Zoe Y Zervides , Nathanael Q E Yap , Maamoun Adra , Hayato Nakanishi , Christian A Than , Francis A Chervenak , Sir Sabaratnam Arulkumaran 

BMC Pregnancy Childbirth,  DOI: 10.1186/s12884-024-06798-0

5.

Discectomy for Lumbar Disc Herniation in Pediatric and Adolescent Populations: A Systematic Review and Meta-Analysis

Christian A Than , Angelique K Valiotis , Abid R Prottoy , Kyle G Alexander , Marios Alogakos , Maamoun Adra , Karen Smayra , Tom J Curtis , Grace E Kim , Hayato Nakanishi , Zaher Dannawi 

Cureus, DOI: 10.7759/cureus.63880

6.

Yield and clinical impact of image-guided bone biopsy in osteomyelitis of the appendicular skeleton: a systematic review and meta-analysis

Karen Smayra , Shahid Miangul , Maria M Witkowiak , Linn K M Persson , Emily E Lugard , Maamoun Adra , Nathanael Q E Yap , Jake Ball , Hayato Nakanishi , Christian A Than , Michael Khoo 

Skeletal Radiology, DOI: 10.1007/s00256-024-04764-7

7.

Anti-VEGF Injections vs. Panretinal Photocoagulation Laser Therapy for Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis

Marie-Michele Macaron , Nader Al Sabbakh , M Zaid Shami , Dennis Akrobetu , Natalie E Bourdakos , Fatma A M Abdulsalam , Hayato Nakanishi , Christian A Than , Sophie J Bakri 

Ophthalmology Retina, DOI: 10.1016/j.oret.2024.08.004

8.

Two- versus one-bag fluid delivery in pediatric and adolescent diabetic ketoacidosis: a systematic review and meta-analysis

Maya L Nasser , Joseph Nasr , Reem B Zalloum , Nathanael Q E Yap , Natalie E Bourdakos , Shahid Miangul , Tara A Betts , Hayato Nakanishi , Christian A Than , Serge Jabbour 

Clinical and experimental Pediatrics,  DOI: 10.3345/cep.2023.01536

1.

Update on the efficacy and safety of intravenous tranexamic acid in hip fracture surgery: a systematic review and meta-analysis

Shahid Miangul , Timothy Oluwaremi , Joe El Haddad , Maamoun Adra , Nathan Pinnawala , Hayato Nakanishi , Reem H Matar , Christian A Than , Thomas M Stewart

European Journal of Orthopaedic Surgery & Traumatology, DOI: 10.1007/s00590-022-03387-9

2.

Platelet-rich plasma versus corticosteroid injections in the management of patients with rotator cuff disease: A systematic review and meta-analysis

Maamoun Adra , Nour El Ghazal , Hayato Nakanishi , Karen Smayra , Sam S Hong , Shahid Miangul , Reem H Matar , Christian A Than , Duncan Tennent 

Journal of Orthopaedic Research,  DOI: 10.1002/jor.25463

3.

Open Versus Laparoscopic Surgery in the Management of Adrenocortical Carcinoma: A Systematic Review and Meta-analysis

Hayato Nakanishi, Shahid Miangul , Rongzhi Wang , Joe El Haddad , Nour El Ghazal , Fatma A Abdulsalam , Reem H Matar , Christian A Than , Benjamin E Johnson , Herbert Chen 

Annals of Surgical Oncology, DOI: 10.1245/s10434-022-12711-w

4.

The effect of exercise post vertebral augmentation in osteoporotic patients: A systematic review and meta-analysis

Christian A Than , Maamoun Adra , Tom J Curtis , Ao Shi , Grace E Kim , Hayato Nakanishi , Reem H Matar , J Mark M Brown , Zaher Dannawi , Belinda R Beck 

Journal of Orthopedic Research , DOI: 10.1002/jor.25631

5.

Safety and efficacy of LA-ERCP procedure following Roux-en-Y gastric bypass: a systematic review and meta-analysis

Baraa Saad , Maya Nasser , Reem H Matar , Hayato Nakanishi , Danijel Tosovic , Christian A Than , Stephanie Taha-Mehlitz , Anas Taha 

Surgical Endoscopy, DOI: 10.1007/s00464-023-10276-7

6.

Technical Success, Sample Adequacy, and Complications of Pediatric Transjugular Liver Biopsy: A Systematic Review and Meta-Analysis

Karen Smayra , Shahid Miangul , Nathanael Yap , Ao Shi , Fatma Abdulsalam , Maamoun Adra , Hayato Nakanishi , Jake Ball , Tara A Betts , Christian A Than , Aneeta Parthipun 

Digestive Diseases and Sciences, DOI: 10.1007/s10620-023-08071-4

7.

The Effects of Deep Brain Stimulation on Mood and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis

Nour El Ghazal , Hayato Nakanishi , Alfonso E Martinez-Nunez , Nader K Al Sabbakh , Omotayo A Segun-Omosehin , Natalie E Bourdakos , Maya Nasser , Reem H Matar , Christian Than , Omar A Danoun , Andrew Johnson 

Cureus, DOI: 10.7759/cureus.44177

8.

Single vs Bilateral Lung Transplant in the Management of Patients With Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

Rania Mansour , Hayato Nakanishi , Nader Al Sabbakh , Nour El Ghazal , Joe Haddad , Maamoun Adra , Reem H Matar , Danijel Tosovic , Christian A Than , Tae H Song 

Transplantation Proceedings , DOI: 10.1016/j.transproceed.2023.08.013

9.

Misgav-Ladach or modified Misgav-Ladach versus Pfannenstiel-Kerr methods for cesarean deliveries: A systematic review and meta-analysis

Natalie E. Bourdakos, Fatma A. M. Abdulsalam, Marie Michele Macaron, Maya L. Nasser, Nathanael Yap, Reem H. Matar, Maamoun Adra, Hayato Nakanishi, Christian A. Than, Sir Sabaratnam Arulkumaran

Reproductive, Female and Child Health, DOI: https://doi.org/10.1002/rfc2.65